Synaptic Plasticity and Translation Initiation

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Synaptic plasticity and translation initiation.

It is widely accepted that protein synthesis, including local protein synthesis at synapses, is required for several forms of synaptic plasticity. Local protein synthesis enables synapses to control synaptic strength independent of the cell body via rapid protein production from pre-existing mRNA. Therefore, regulation of translation initiation is likely to be intimately involved in modulating ...

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ژورنال

عنوان ژورنال: Learning & Memory

سال: 2004

ISSN: 1072-0502

DOI: 10.1101/lm.79004